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Gatan K3 direct electron detector positioned post a Gatan BioQuantum energy filter (Gatan, Pleasanton, California, USA), operated in a zero-loss mode with a slit width of 25 eV was used to acquire dose fractionated images of the samples with a 100 m objective aperture

It will be important to determine the roles of GLP-1 agonisms as compared to SGLT2i in this patient population

One medication is rarely enough for sustained control over decades

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Delivery of insulin directly to the CNS is possible through intranasal devices, which, in early trials, has been shown to improve cognition compared to placebo in AD patients [159]